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Pharma Sector: Few Newsmakers Of The Week - Merck, Novartis ...

...The torcetrapib drug trial was halted because of an unexpected number of deaths and other complications in the trial.

Bringing thirteen compounds into clinical testing in just over three years is no mean achievement for a company, which has just barely crested the $1 billion mark in market capitalization.

The accomplisher of this unique achievement is Exelixis.

The company experienced a setback with its experimental cancer drug, XL999 last year as it had to halt enrollment of new patients in its phase II trial with XL999 after a safety monitoring board noticed an elevated level of serious cardiovascular adverse events.

On Tuesday, the FDA allowed Exelixis to resume testing of XL999, which had been kept on partial hold since last December.

The company also submitted an application to the FDA seeking approval to commence human clinical trials with XL765, a drug candidate for non-small cell lung cancer.

After years of touting the effectiveness of Dexanabinol in treating Traumatic Brain Injury or TBI, drug developer Pharmos in December 2004, announced that Dexanabinol was not found to be materially effective in Phase III testing.

Pharmos almost got crushed with its stock price plummeting 66%, back then.

The field of biotechnology is fraught with risk and disappointment and biotech...

Team Lean A whole lot of weight lost

... “Remember, this was not a controlled study,” Scott said.

“When we looked at all of the values and just put it in as an average, the average But the average triglyceride went down 30 points.

And that’s an important value, too.

So when you get your results, if you have any questions, take them to your physician and whatever you do, keep up the good work.” Team Lean 2008 Peak said another Team Lean will begin Jan.

3, 2008, and there will be a six-month weigh-in that will award $250 to the top 20 Team Lean participants who keep losing weight.

“We started with 190,000 pounds [total participants’ combined weights],” said Jim Peak, Memorial Hospital CEO.

“Team Lean lost 16,154 pounds; that’s over eight tons,” Peak said.

“That’s the equivalent of two Hummers, 68 refrigerators, five Toyota Camry’s, 32 John Deere mowers, 22 Harley-Davidson Road Kings, or the same as 80 Jim Peaks.” He said 302 people lost from 10 to 20 percent of their body weight.

Twelve people lost over 20 percent of their body weight.

He asked the crowd to give itself another round of applause.

He also especially thanked Cathy Willis and Leslie Stone who coordinated t...

The Way We Age

...There is, he said, "no single, common cellular mechanism to the aging process." Our bodies accumulate lipofuscin and oxygen free-radical damage and random DNA mutations and numerous other microcellular problems.

The process is gradual and unrelenting.

"We just fall apart," he said.To read comments on this story, and to post your own thoughts, click here.Key words: aging, age, elderly, mechanisms of aging, wearing-out, damage accumulation, New Yorker, Atul Gawande, Leonid Gavrilov, redundancy, reliability theory, systems failure, Felix SilverstoneHome:Longevity Science: The Way We Agehttp://longevity-science.blogspot.com/atom.xml Mprize Fund $4,437,733 SENS Fund $4,097,970 Contribute High Quality Supplements & Vitamins Email Updates!

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