Cholesterol

Existing drugs for obesity work by reducing appetite or preventing the absorption of fat.

In earlier research, Dr Evans identified the receptor that tells cells when to burn fat, when to store it and regulates muscle development.

Through genetic engineering, he created a family of mice born with an innate resistance to weight gain and twice the physical endurance of normal mice.

In the latest research, Dr Evans and colleagues have found a drug that can activate the receptor switch in fat cells temporarily, opening up the possibility of a one-a-day pill for fully grown adults who needed to increase their energy expenditure and lose weight.

He said: "Too few people get an ideal amount of exercise.

Having access to an exercise pill would improve the quality of muscles, and increase the burning of energy or excess fat [lowering] the risks of heart disease and diabetes." Also in this section Mental Health Campaign: Susan begged for help, instead she was sent to prison Scientists demand inquiry over Wi-Fi Cannabis harms mental health, scientists warn Hospitals fail to halt spread of superbug that kills 4,000 a year Alarm at significant drop in number of NHS workers A A A .article {visibility: visible;} Editor's Choice Sir Mark Tully Broadcaster and author's unending journey through India ...

and Burger King Holdings Inc.

have also said they will phase out trans fat from their products.

KFC said the change in cooking oils will not change how its fried chicken tastes.

"We have safeguarded the recipe and the flavor profile," said Doug Hasselo, KFC’s chief food innovation officer.

Hasselo said the new cooking oil costs more, but the chain will absorb the extra expense without passing it along to customers.

The zero grams trans fat items at KFC also include its potato wedges.

Some of KFC’s non-fried items still contain trans fat, including biscuits, pot pies, macaroni and cheese, and some desserts.

The company said it’s working to remove trans fat from those items.

KFC was unveiling television advertising Monday to promote its switch to cooking oil without trans fat.

KFC stores will put up signs touting the conversion, and the chicken buckets will carry the health message within a week or two.

The company won praise from the Center for Science in the Public Interest, a consumer group that pushed for KFC to switch to a healthier cooking oil.

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She said she was concerned enough that she would consider me for gastric bypass or would wire my jaws shut.

I remember going home and I cried and cried." PHOTOS: Dieter drops pounds and insecurities So in November 2000, Rhoads went to a Weight Watchers meeting and lost 16 pounds the first week.

"It was like the jump-start I needed for motivation," she says.

On Feb.

14, 2004, she met her goal weight of 160 pounds, and she has kept it off since.

Rhoads is one of more than a dozen readers who is being profiled in the fourth annual USA TODAY Weight-Loss Challenge.

This year's challenge, which runs every Monday through May, focuses on people who have succeeded at losing and maintaining their weight.

FORUM: Comment on Rhoads' story below and share your experiences here Rhoads says she was an emotional eater who started overeating as a teenager to avoid unwanted attention from older men.

"When I was an adolescent, several men commented on my developing body inappropriately, and it scared me," she says.

"To protect myself, I ate.

Food was safe.

"I was hiding in plain view.

When you are that big, people don't look at you.

They don't make eye contact." During the years she was losing weight, Rhoads came to terms with those emotions.

She also made changes she still practices: She keeps a daily food journal, exercises regularly and limits foods high in sugar and saturated (...