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Intestinal Metabolic Function Impaired By High Insulin Levels

..."Now that we know high levels of insulin are associated with altered intestinal chylomicron metabolism and a build up of these particles in the blood vessel walls, our next step is to use this animal model to look closer at the cellular mechanisms and try to figure out how this happens," said Dr.

Donna Vine, a nutritional scientist at the U of A and co-author of the paper in Atherosclerosis.

High insulin levels are caused by excessive consumption of sugar and fatty foods.

Perpetually high insulin levels can lead to insulin resistance, which predisposes individuals to develop Type 2 diabetes and increased risk of cardiovascular disease.

Traditionally, scientists have believed cardiovascular disease was connected to increased levels of low-density lipoprotein (LDL) However, Vine and her colleagues believe high levels of intestinal chylomicron It is estimated fifty per cent of cardiovascular disease events occur in the presence of normal LDL-If chylomicron levels...

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