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Possible New Cancer Treatment? Antifungal Drug Stops Blood Vessel ...

...It turns out that itraconazole can block the same enzyme in blood vessels, but the researchers aren't positive if that's the reason blood vessels stop growing, because related antifungal drugs had much lower inhibitory effect.

"Our screening test did show that "Itraconazole can be taken orally for fungal infection, and therefore oral delivery may work for angiogenesis as well," Liu notes.

The research was funded by the Johns Hopkins School of Medicine, the Johns Hopkins Fund for Medical Discovery, the Johns Hopkins Malaria Research Institute, the Keck Foundation, and the Flight Attendant Medical Research Institute Fund.

Authors on the paper are Curtis Chong, Jing Xu, Jun Lu, Shridhar Bhat, David Sullivan Jr.

and Jun O.

Liu, all of Johns Hopkins.

Note: This story has been adapted from a news release issued by Johns Hopkins Medical Institutions.

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